牟晓东

文章来源: 发布时间:2023-07-04浏览次数:

姓名:牟晓东

博士生导师

职称:教授

联系方式:18764037380

研究方向:

1. 细胞衰老机制和抗衰老药物的作用机制

2. 干细胞及外泌体的医疗应用

3. 抗肿瘤药物的靶向递送

主要学术任职:

1. 山东省生物化学学会, 理事

2. 山东省细胞生物学会, 理事

主要获奖情况(包括作为指导教师):

1.

2.

主持科研课题:

1. 山东省自然科学基金面上项目,ZR2022MC025, 细胞核被膜蛋白Sun1/2 对细胞天然免疫相关衰老进程的调控机制, 2023.01 - 2025.12,10万元,主持

近五年代表性论文(限第一作者和通讯作者):

1. Lei Liu; Xianlin Yue; Zewei Sun; William S. Hambright; Jianming Wei; Ying Li; Polina Matre; Yan Cui; Zhihui Wang; George Rodney; Johnny Huard; Paul D. Robbins; Xiaodong Mu*; Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells, Journal of Cachexia, Sarcopenia and Muscle, 2022, 13(6): 3137-3148 (通讯作者)

2. Lei Liu; Xianlin Yue; Zewei Sun; William S. Hambright; Qi Feng; Yan Cui; Johnny Huard; Paul D. Robbins; Zhihui Wang; Xiaodong Mu*; Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle, Aging, 2022, 14(19): 7650-7661 (期刊论文) (通讯作者)

3. Xiaodong Mu*; Chieh Tseng; William S Hamsbright; Polina Matre; Chi-Yi Lin; Palas Chanda; Wanqun Chen; Jianhua Gu; Sudheer Ravuri; Yan Cui; Ling Zhong; John P Cooke; Laura J Niederhofer;Paul D Robins; Johnny Huard*; Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Guilford Progeria Syndrome, Aging Cell, 2020, 19(8):e13152 (第一作者)

4. Xiaodong Mu; Chi-Yi Lin; William S Hamsbright; Ying Tang; Sudheer Ravuri; Aiping Lu; Polina Matre; Wanqun Chen; Xueqin Gao; Yan Cui; Ling Zhong; Bing Wang; Johnny Huard*; Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice, Aging (Albany NY), 2020, 12(24): 24853-24871 (第一作者)

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