王洪亮

文章来源:药学院 发布时间:2024-03-31浏览次数:

姓名:王洪亮

硕士生导师

职称:副教授

联系方式:13220585201    邮箱:hliang_18@sdfmu.edu.cn


研究方向:

1. 有机化学反应机制研究

2. 计算机辅助手性药物分子设计


主要学术任职:

担任J. Phys. Chem. A, J. Org. Chem., Catal. Sci. Technol. 等杂志审稿人


主要获奖情况(包括作为指导教师):

2023年,荣获山东省泰山学者(青年专家)称号


主持科研课题:

1. 国家自然科学基金青年项目,22203051钴催化不饱和烃硼氢化反应机理和选择性的理论研究2023/01-2025/1230万元,在研,主持

2. 山东省自然科学基金青年项目,ZR2021QB047钴催化不饱和烃硼氢化反应机理的理论研究2022/01-2024/1215万元,在研,主持

3.69批中国博士后科学基金资助面上项目2021M6919172021/05-2022/108万元,结题,主持

4.65批中国博士后科学基金资助面上项目2019M6520562019/05-2020/128万元,结题,主持

5. 国家自然科学基金重大研究计划(培育项目)92156008氮、磷、硅等杂原子手性中心的不对称氧化构筑2022/01-2024/1270万元,在研主要参与人

6. 国家自然科学基金面上项目21773139木质素模型化合物在酸性咪唑离子液体中溶解和降2018/01-2021/1265万元,结题主要参与人


近五年代表性论文(限第一作者和通讯作者):

1. Peng Lu#; Hongliang Wang#, Yihui Mao, Xin Hong*, Zhan Lu*, Cobalt-Catalyzed Enantioconvergent Hydrogenation of Minimally Functionalized Isomeric Olefins, J. Am. Chem. Soc. 2022, 144(38): 17359–17364.

2. Chenhui Chen#, Hongliang Wang#, Tongtong Li#, Dongpo Lu, Jiajing Li, Xie Zhang, Xin Hong*, and Zhan Lu*, Cobalt-Catalyzed Asymmetric Sequential Hydroboration/Isomerization/Hydroboration of 2-Aryl Vinylcyclopropanes, Angew. Chem. Int. Ed. 2022, 61: e202205619.

3. Jun Guo#, Hongliang Wang#, Shipei Xing, Xin Hong*, Zhan Lu*, Cobalt-Catalyzed Asymmetric Synthesis of gem-Bis(silyl)alkanes by Double Hydrosilylation of Aliphatic Terminal Alkynes, Chem, 2019, 5(4): 881–891.

4. Bo Zhou#, Hongliang Wang#, Zhong-Yan Cao, Jia-Wen Zhu, Ren-Xiao Liang, Xin Hong*, Yi-Xia Jia*Dearomative 1,4-Difunctionalization of Naphthalenes via Palladium-Catalyzed Tandem Heck/Suzuki Coupling Reaction, Nat. Commun., 2020, 11: 4380.

5. Yuezhou Liu#, Hongliang Wang#, Liqing Shangguan, Peiren Liu, Bingbing Shi,* Xin Hong* and Feihe Huang* Selective Separation of Phenanthrene from Aromatic Isomer Mixtures by a Water-Soluble Azobenzene-Based Macrocycle, J. Am. Chem. Soc. 2021, 143(8): 3081–3085.

6. Yuezhou Liu#, Hongliang Wang#, Peiren Liu, Huangtianzhi Zhu, Bingbing Shi*, Xin Hong* and Feihe Huang* Azobenzene-Based Macrocyclic Arenes: Synthesis, Crystal Structures and Light-Controlled Molecular Encapsulation and Release, Angew. Chem. Int. Ed. 2021, 60(11): 57665770.

7. Hongliang Wang, Shuo-Qing Zhang*, Xin Hong*, Computational studies on Ni-catalyzed amide C–N bond activation, Chem. Commun., 2019, 55(76): 1133011341.

8. Hongliang Wang, Mengmeng Dong, Chengbu Liu, Dongju Zhang*, Theoretical insight into the Zinc(II)-catalyzed synthesis of 2-indolyltetrahydroquinolines from N-propargylanilines and indoles: a cross-dehydrogenative coupling with temporally separated catalytic activity, Catal. Sci. Technol., 2018, 8(7): 19972007.  

9. Hongliang Wang, Chengbu Liu, Dongju Zhang*, Decisive effects of solvent and substituent on the reactivity of Ru-catalyzed hydrogenation of ethyl benzoate to benzyl alcohol and ethanol: a DFT study, Mol. Catal., 2017, 440: 120132.

10. Yasheng Zhu#, Hongliang Wang#, Gang Wang, Zehua Wang, Zhaopeng Liu*, Lei Liu*, Enantioselective Construction of Single and Vicinal All-Carbon Quaternary Stereocenters through Ion-Pair-Catalyzed 1,6-Conjugate Addition, Org. Lett. 2021, 23(18): 72487253.

11. Peiren Liu#, Hongliang Wang#, Hong Zeng, Xin Hong*, Feihe Huang*A [15]paracyclophenone and its fluorenone-containing derivatives: syntheses and binding to nerve agent mimics via aryl-CH hydrogen bonding interactionsOrg. Chem. Front., 2021, 8(1): 2531.

12. Chenhui Chen#, Hongliang Wang#, Yufeng Sun, Jiayan Cui, Jianbo Xie, Yang Shi, Shijia Yu, Xin Hong*, Zhan Lu*, Iron-Catalyzed Asymmetric Hydrosilylation of Vinylcyclopropanes via Stereospecific C-C Bond Cleavage, iScience, 2020, 23(4): 100985.

13. Hongliang Wang, Chengbu Liu, Dongju Zhang*, Mechanistic study on the Rh(III)-catalyzed synthesis of indolines via selective O-atom transfer of arylnitrones: origins of the regioselectivity and the improved yield with pivalic acid additive, J. Organomet. Chem., 2018, 854: 1526.







格式1. Liming Tan#, Kelvin Xi Zhang#, Matthew Y. Pecot, Sonal Nagarkar-Jaiswal, Pei-Tseng Lee, Shin-ya Takemura, Jason M. McEwen, Aljoscha Nern, Shuwa Xu, Wael Tadros, Zhenqing Chen, Kai Zinn, Hugo J. Bellen, Marta Morey*, S. Lawrence Zipursky*, Ig Superfamily Ligand and Receptor Pairs Expressed in Synaptic Partners in Drosophila, Cell, 2015, 163



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